ea0032p655 | Male reproduction | ECE2013
Vignozzi Linda
, Gacci Mauro
, Cellai Ilaria
, Santi Raffaella
, Corona Giovanni
, Morelli Annamaria
, Rastrelli Giulia
, Comeglio Paolo
, Sebastianelli Arcangelo
, Maneschi Elena
, Nesi Gabriella
, De Nunzio Cosimo
, Tubaro Andrea
, Mannucci Edoardo
, Carini Marco
, Maggi Mario
Background: Metabolic syndrome (MetS) and benign prostate hyperplasia (BPH) are often comorbid. Chronic inflammation, a determinant pathogenic factor for BPH, is a putative link between the two conditions.Methods: In a multi-center cohort of BPH patients (n=244) who underwent prostatectomy, we evaluated whether MetS is associated with prostatic inflammation in BPH specimens. In addition, we investigated the in vitro inflammatory effects...